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THE CRIMSON STAIN MYSTERY
Featuring MAURICE COSTELLO and ETHEL GRANDIN
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Dr. Burton Montrose, a famous scientist, discovers a biological element which he believes will improve the mental faculties of the human race. Instead, when tested on a few human subjects, the discovery reacts, turning them into cruel and bloodthirsty murderers. Serial killer Pierre LaRue, called the "Crimson Stain" because the whites of his eyes are red, appears and takes charge of them as his gang and targets a new victim in every episode.

Young Florence Montrose, daughter of the scientist, ends up in the middle of a lot of the trouble at hand and newspaperman Harold Stanley (Maurice Costello, Drew Barrymore's great-grandfather) tries to protect her from La Rue's devilish advances.